Unit Size: 2 mg per vial
Sequence: Tyr-Gln-Pro-Pro-Ser-Thr-Asn- Lys-Asn-Thr-Lys-Ser-Gln-ArgArg-Lys-Gly-Ser-Thr-Phe-Glu- Glu-Arg-Lys
Molecular formula: C121H200N420O39
Molecular Weight: 2888 16 g/mol
CAS number: N/A
Physical State: Lyophilized Powder
Market Status: Research use only
Pegylated Mechano Growth Factor (PEG MGF) is a variant of the IGF-1 (insulin-like growth
factor-1), which stimulates myoblasts division and allows for muscle fibers to fuse and
mature. This is a process required for growth of adult muscle. The difference between IGF-1
and MGF is that MGF stimulates myoblasts division through stimulation of different
Pegylated MGF is more bioavailable. Injected 2-3 times per week, it maintains effective
concentration for a long period.
MGF has a huge role to play, and is administered to those with muscle wasting diseases and
for those who are elderly and have lost muscle mass.
The PEG-MCF helps with the improvement of muscle growth. It also helps the damaged
muscles to recover.
According to studies, MGF can improve muscle growth by 25% in as short as 3 weeks. The
Pegylated Mechano Growth Factor benefits may include:
Reduced body fat I Improved endurance
Better immunity defenses
Reduce bad cholesterol
Triggers nitrogen retention
Improves protein synthesis
Neurological research has shown that utilizing PEGylated MGF resulted in a longer more
stable acting version of the MGF peptide in serum/blood.
PEGylation can improve performance and dosing convenience of peptides, proteins,
antibodies, oligonucleotides and molecules by optimizing pharmacokinetics, increasing
bioavailability, and decreasing immunogenicity and dosing frequency.
PEGylation also can increase therapeutic efficacy by enabling increased drug concentration,
improved biodistribution, and longer dwell many small times at the site of action. As a result,
therapeutic drug concentrations can be achieved with less frequent dosing – a significant
benefit to patients who are taking injected drugs. The PEG itself does not react in the body
and is very safe. PEG has been approved by the US Food and Drug Administration (FDA) as
a base or vehicle for use in foods and cosmetics and in injectable, topical, rectal and nasal
pharmaceutical formulations, PEG has demonstrated little toxicity, is eliminated intact by the
kidneys or in the feces and lacks immunogenicity.
PEG-MGF is anabolic and would be best if administered after a workout or during rest days.
This is important to remember because if you use this before a workout, it will not work
effectively since IGF-1 will bind to the receptors. The best dosage according to experienced
users is from 100 mcg per injection up to 1000 mcg. One cycle is equivalent to 5 or 6 weeks.
During a cycle, this will be injected 2 or 3 times a week. It should be injected subcutaneously
to follow the natural MGF secretion. There are also users who inject it intramuscularly and
bilaterally which is better for specific muscle growth.
There are not so many Pegylated Mechano Growth Factor side effects because this has not
been thoroughly studied yet. However, there are reports about the feeling of pain and
irritation at the injection site. It has an itchy and sore feeling according to users who have
Store under 2…8°C. Do not freeze. Protect from direct sunlight.
Manufactured by: Hilma Biocare
Distributed by: Rein Farmacie, Belgium